This is something I wrote years and years ago, but which slipped through the great blog reorganisation a couple of years ago, back when I thought I’d be able to find the time for a whole blog about cancer biology. So I’ll dump it here for safe keeping… This post […]
This is another archival report, originally written for the old blog in 2008. Here’s an interesting one: Genesis chapter 30. If you think Darwin got inheritance wrong, try the Bible. 30:28 And he [Laban] said, Appoint me thy wages, and I will give it. 30:29 And he said unto him, […]
This is another archival repost, written for the old blog in January 2008. The central dogma of molecular biology, first described by Francis Crick in 1958, describes the flow of information between DNA, RNA, and proteins.[1] The central dogma is interesting, but I believe that its use in teaching is […]
This is another archival repost first written for the old blog in 2007. On Monday I mentioned John Maynard Smith’s videos at People’s Archive. They really are marvelous, and you should watch them all. One of the topics he discusses is horizontal gene transfer in bacteria, a subject I discussed […]
This post probably doesn’t quite work, but at At War With The Motorist I continue the thread on shared space by considering the mechanism by which it works: risk compensation — the idea that when traffic management is ripped out, road users will perceive the road to be more risky […]
This was originally written a year ago on a now disused blog. I’m reposting it here because I enjoyed writing it so much that I wouldn’t want it to disappear. People love a good argument with Richard Dawkins. So many people are so desperately seeking reassurance that he is wrong, […]
Another in the ongoing project to archive posts from an old blog – this one from february 2009. Not in the television programme — well, I don’t know, I haven’t seen it yet due to pesky tennis fans capturing the remote control — but in the Simon Mayo interview (page […]
This is another archival repost from the old blog, first published way back in March 2008. I’ve been following CBC’s How To Think About Science series, and caught the Evelyn Fox Keller episode the other day. It was interesting, but there were a couple of issues that I just can’t […]
-or- “(One of many reasons) Why genomics matters” This is an archival repost which was originally posted on the old blog in feb 2009, during the Darwin 200 celebrations. In chapter 14 of The Origin Darwin discussed embryological stages and their utility in classification. This utility derives from the fact […]
This post is part of a series on The Origin Of Species. It was originally posted on the old blog in feb 2009, during the Darwin 200 celebrations. In chapter nine, Darwin takes a long look at hybrids. And I mean a long look: he can really go off on […]
This post is part of a series on The Origin Of Species. It was originally posted on the old blog in feb 2009, during the Darwin 200 celebrations. It has been noted enough times now that Darwin knew nothing of genetics, and I already described Darwin’s bizarre Lamarckian hypothesis for […]
This post is part of a series on The Origin Of Species. It was originally posted on the old blog in feb 2009, during the Darwin 200 celebrations. In Chapter one of the Origin, Darwin discusses inheritance and variation. It’s an interesting choice for a starting point, because as everyone […]
This is another archive repost from the old blog, written in aug 2008. The psychologist Oliver James was on The Late Edition a couple of weeks ago.[1] His argument was unconvincing and his behaviour unimpressive. So I took a quick look at his website. He offers for download a Radio […]
This is an archival repost originally written on the old blog in 2008. Hah! Made you look! No, but seriously… The schizophrenic argument of the creationists goes something like this (my paraphrasing): How can we believe anything these scientists say when they keep changing what they say to accommodate the […]
This is another archival repost, originally written for the old blog in May 2008. Darwin’s 1837 phylogeny, with root and branches. I’ve talked about Horizontal Gene Transfer (HGT) on the blog a few times before, particularly in the context of bacteria acquiring genes for things like antibiotic resistance, and in […]
This is an archive from the old blog, originally written in 2008. Regular readers may have noticed that I get rather annoyed by the casual use of the word “chemical” to mean “synthetic chemical”, and the use of the naturalistic fallacy (natural good, chemical bad) that is associated with this […]
This is another archival repost from the old blog — this one from January 2008. The post is part five in a series. The series so far can be found here. In the first installment of Sunday Syndrome I used the example of Prader-Willi Syndrome. This week we’ll bring in […]
This is another archival repost from the old blog — this time from Nov 2007. The post is part four in a series. The series so far can be found here. So far in the Sunday syndrome column, we’ve been talking in terms of the all-or-nothing loss (or gain) of […]
This is an archive from the old blog, originally written in 2007. The “Thursday Paper” column on the blog is for reporting on a recently published peer-reviewed research. Apologies if this one isn’t so polished, but I have a train to catch. It would appear to be medical genetics week […]
This post is an archive from the old blog, originally written in 2007. I’ve been discussing in the “Sunday syndrome” column various disorders caused by genetic aberrations, but I haven’t really explained how such aberrations occur. There are several different types of aberration that occur, and several different mechanisms that […]
This is another archival repost from the old blog, this time from november 2007. The post is part three in a series. The series so far can be found here. Some causes of disease are heritable genetic aberrations. Others are diet, pathogens, trauma, and similar environmental factors. One might get […]
This is another archival repost from the old blog, originally written in oct 2007. Evolution, from the point of view of the geneticist, is the change in allele frequencies that occurs in populations over time. New alleles are created by random mutation, and others slowly disappear through natural selection or […]
This is another archival repost, this time from oct 2007. The post is part two in a series. The series so far can be found here. Knowing how and why things go wrong tells us a lot about how and why things work when they go right. Indeed, this is […]
This is another archival repost, originally from oct 2007. Are you an addict? I bet you are (I saw you gambling addicts coming!). It might be coffee, chocolate, or tobacco, rather than alcohol, heroin, or self-harm, and you might not be wasting away because of it, but you’re probably addicted […]
This is another archival repost from the old blog, originally from oct 2007. It’s not healthy to bottle up your worries and stress. That’s why all the best comedy throughout the ages has dealt with the tough issues that worry us. It’s why doctors make jokes about diseases and pathologists […]